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KMID : 0378019620050030095
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New Medical Journal
1962 Volume.5 No. 3 p.95 ~ p.101
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Pneumocystis Carinii Pneumonia
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宋玧奎/Song, Yun Kyu
李源順/李桂浩/申勝雨/Lee, Won Soon/Lee, Ke Ho/Shin, Sung Woo
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Abstract
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Twenty cases of Pneumocystis carinii pneumonias have been reported. They occurred in one to four month old infants in three separate orphanages. Twelve cases occurred in three month old infants, which is 60 percent of all cases. The sexual distribution is eighteen female and two male. The distribution may be influenced by the large percentage of females in Korean orphanages. The clinical symptoms observed were tachypnea, cyanosis, cough in most cases, and mild, moist rales in a few cases.
The roentgenological findings are classified in three types; the first type is bronchopneumonic, with fine, mottled density throughout both lungs. The second type is bilateral, with scattered, lobular pneumonic patchy density. The third type is bilateral lobar, with pneumonic, confluent, diffuse density. The peculiar findings of these cases were found combined with spontaneous unilateral pneumothorax, the lobular and lobar pneumonic type. The features of lung finding was differentiated according to the stage of the disease.
The diagnosis was made after an autopsy in all cases, The chief pathological finding was an interstitial pneumonia that was characterized by eosinophilic honey-combed foamy material in the alveoli, and moderate to severe infiltration of large mononuclear cells including plasma cells. Cysts of Pneumocystis carinii were demonstrated within the eosinophilic foamy material by Gridley´s fungus stain in all cases. It is of interest that the Pneumocystis carinii was found in the bronchi and bronchioles, as well as mucopurulent bronchitis and bronchiolitis in one case. No specific therapy has been found effective. Treatment was given for symptomatic relief only.
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